The wide variety of emerging technologies could revolutionize an array of applications, and this session explores design techniques to maximize system-level advantages from these device technologies. The first paper presents exciting experimental results that demonstrate techniques to overcome CNTFET process variations. This is followed by a framework to minimize the power consumption of optical and electrical on-chip signals through device-system co-design. Next paper discusses techniques to decrease peak switching current, and therefore improve total energy efficiency, through the use of phase change materials. The session concludes with a proposal to use Gaussian I-V transistors for ultra-low power speech processing.